Evolving targets for lipid‐modifying therapy

Evolving targets for lipid-modifying therapy

The pathogenesis and progression of atherosclerosis are integrally connected to the concentration and function of lipoproteins in various classes. This review examines existing and emerging approaches to modify low-density lipoprotein and lipoprotein (a), triglyceride-rich lipoproteins, and high-density lipoproteins, emphasizing approaches that have progressed to clinical evaluation. Targeting ...

Molecular Targets for Endometriosis Therapy: Where We Are and Where We Are Going?

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Choosing Targets for Gene Therapy

Newest Targets for Anticonvulsant Agents: An Overview

Epilepsy is a neurological condition characterized by recurrent seizures influencing about 1% of the worldwide population. Despite much progress in understanding the pathogenesis of epilepsy, the molecular basis of human epilepsy still remains unclear. Common approaches for pharmacotherapy of epilepsy are still directed towards controlling the symptoms and suppression of seizures. Clinical use ...

Identifying Molecular Targets for Cancer Therapy

Within cancer research a molecular target is a specific molecular attribute in a cancer cell or tumor tissue that may play a role in promoting disease progression. There are many of these molecular attributes present in cancer biology and they represent events for therapeutic intervention. However, the major challenge for cancer therapy is selecting the right time to exploit a molecular target,...